Rad9 (Drosophila RAD9) review notes

Literature journal

• Isoforms and localization: PMID:22666434; PMID:22666434.
• 9-1-1 complex: PMID:22666434
• Deep research (falcon) summarizes a 2025 Rad9 mutant study: [file:DROME/Rad9/Rad9-deep-research-falcon.md "Thus Rad9B provided the convincing rescue of efficient early meiotic break resolution in these assays"]; Brca2 association from ovary co-IP (Klovstad 2008).

Curation decisions

• Core: 9-1-1 clamp subunit directing complex localization (MF approximated by GO:0030674) in DNA damage checkpoint signaling.
• 3'-5' exonuclease activity (ISS) marked over-annotated: no fly evidence; contested mammalian in vitro activity transferred to a clamp subunit.
• Not curated here: the 2025 isoform-rescue study (DOI 10.1016/j.dnarep.2025.103833) is not yet in GOA or the publication cache.