RPE1 notes (ribulose-phosphate 3-epimerase, YJL121C, POS18)

• Activity: [UniProt:P46969 "Reaction=D-ribulose 5-phosphate = D-xylulose 5-phosphate;"]; extracts PMID:8929392
• Null: PMID:8929392
• Oxidative stress: pos18 = rpe1 PMID:8879247; PPP mutants H2O2-sensitive (same paper).
• Metal: [UniProt:P46969 "Note=Binds 1 divalent metal cation per subunit. Active with Co(2+),"] (by similarity to human); zinc ion binding RCA from zinc-proteome bioinformatics PMID:30358795 -> non-core; in vivo metal identity unresolved.
• Cytosol TAS from 13C flux study PMID:11298766.
• Generic 'carbohydrate metabolic process': IBA kept non-core (deep PANTHER node includes other phosphosugar epimerases, e.g. P32719); IEA MODIFY -> GO:0009052. 'racemase and epimerase activity, acting on carbohydrates' IEA MODIFY -> GO:0004750.
• Core: GO:0004750, GO:0009052, cytosol.