EBF1 (At2g25490, Q9SKK0) curation notes

2026-10-05 session (ethylene_signaling module)

• Deep research (falcon) failed (exit code 1); review based on cached literature and UniProt.
• F-box/SCF: [PMID:15090654 "two F-box proteins, EBF1 and -2, that work coordinately in SCF complexes to repress ethylene action"; "EBF1 and -2 interact directly with ethylene insensitive 3 (EIN3)"].
• EIN3 degradation: PMID:14675532
• Genetics: PMID:14675533.
• Paralog roles: PMID:17307926.
• Ethylene downregulates EBF1/2 protein PMID:20647342 and EIN2 represses EBF1/2 translation via 3' UTR PMID:26496607; EBF2 translational control PMID:26496608.
• Localization: nucleus and cytoplasm PMID:23166809.
• Protein binding: 33 IPI rows. EIN3 and ASK/CUL1 partners -> MODIFY to GO:1990756 ubiquitin-like ligase-substrate adaptor activity; high-throughput interactome partners (PMID:32612234) -> REMOVE.
• Possible identifier issue: IPI with P43291 (SRK2A/SnRK2.4, synonym "ASK1") from PMID:14675532/14675533 likely intended SKP1A/ASK1 (Q39255); flagged, removed as uninformative protein binding.