Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Gene Ontology annotation based on curation of immunofluorescence data

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

SLC24A5 encodes a trans-Golgi network protein with potassium-dependent sodium-calcium exchange activity that regulates human epidermal melanogenesis.

Dynamic and transient interactions of Atg9 with autophagosomes, but not membrane integration, are required for autophagy.

ZNRF2 is released from membranes by growth factors and, together with ZNRF1, regulates the Na+/K+ATPase.

Dynamics of the rhomboid-like protein RHBDD2 expression in mouse retina and involvement of its human ortholog in retinitis pigmentosa.

A proteome-scale map of the human interactome network.

Regulation of post-Golgi LH3 trafficking is essential for collagen homeostasis.

Molecular cloning and expression of a novel human trans-Golgi network glycoprotein, TGN51, that contains multiple tyrosine-containing motifs.

AP-2 directly binds some endocytic cargo

F- and N- BAR domain proteins bind the clathrin-coated pit

CLASP proteins and cargo are recruited to the nascent clathrin-coated pit

Clathrin recruits PIK3C2A

Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2

SNX9 recruits components of the actin polymerizing machinery

BAR domain proteins recruit dynamin

SYNJ hydrolyze PI(4,5)P2 to PI(4)P

Endophilins recruit synaptojanins to the clathrin-coated pit

HSPA8-mediated ATP hydrolysis promotes vesicle uncoating

Clathrin recruits auxilins to the clathrin-coated vesicle

Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle

Dynamin-mediated GTP hydrolysis promotes vesicle scission

Dissociation of clathrin-associated proteins

Dissociation of AAK1 and dephosphorylation of AP-2 mu2

RAB5 and GAPVD1 bind AP-2

FAM20C phosphorylates FAM20C substrates

Sorting of secretory proteins at the trans-Golgi network by human TGN46.

Primate homologues of rat TGN38: primary structure, expression and functional implications.

Distinct compartmentalization of TGN46 and beta 1,4-galactosyltransferase in HeLa cells.

Specificity of interaction between adaptor-complex medium chains and the tyrosine-based sorting motifs of TGN38 and lgp120.

Identification of different itineraries and retromer components for endosome-to-Golgi transport of TGN38 and Shiga toxin.

UniProt entry O43493 (TGON2_HUMAN)