PP_4332 notes

Curation session 2026-11-03

Deep research attempts: just deep-research PSEPK PP_4332 --provider perplexity failed ("Provider 'perplexity' not available"); just mod-description-deep-research PSEPK PP_4332 skipped (no MOD provider configured for PSEPK). No provider deep-research file exists for this gene; review based on the UniProt record, cached publications and the project synthesis projects/P_PUTIDA/deep-research/PSEPK__bacterial_chemotaxis_signal_transduction__ppu02030-deep-research-openscientist.md.

TrEMBL entry Q88EX0 (PE 4). Single CheW domain; CheW subfamily (IPR039315; PANTHER PTHR22617:SF23). Adjacent paralog PP_4333 (CheW domain protein) unresolved.
- E. coli CheW (P0A964): PMID:11923283, PMID:11923283.
- PMID:21606342

Decisions: cytosol ACCEPT; chemotaxis ACCEPT; signal transduction MODIFY -> GO:0000160; NEW GO:0060090 molecular adaptor activity, ISS with UniProtKB:P0A964, ref PMID:11923283 (module MF supported). No KT2440 PP_4332 mutant data in cache.
Gene symbol kept as PP_4332 (UniProt gives no gene name).