Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Combined Automated Annotation using Multiple IEA Methods
MexAB-OprM hyperexpression in NalC-type multidrug-resistant Pseudomonas aeruginosa: identification and characterization of the nalC gene encoding a repressor of PA3720-PA3719.
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PA3721 (nalC) negatively regulates PA3720-PA3719; MexAB-OprM effects are via PA3719.
"Thus, the nalC (PA3721) mutation serves only to enhance PA3720-PA3719 expression"
Pentachlorophenol induction of the Pseudomonas aeruginosa mexAB-oprM efflux operon: involvement of repressors NalC and MexR and the antirepressor ArmR.
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NalC binds an inverted repeat upstream of PA3720-armR; PCP releases it.
"The NalC binding site was localized to an inverted repeat (IR) sequence upstream of PA3720-armR"
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A nalC mutant shows increased PA3720-armR expression.
"although the mutant showed the expected increase in PA3720-armR expression compared with its wild type parent K767"
nalC (PA3721) review notes