ift-20 (Q8TA52, IFT20 ortholog) notes
Deep research status
just deep-research-falcon worm ift-20 --fallback perplexity-lite was run on 2026-10-08. Falcon timed out and the perplexity fallback was unavailable, so there is no deep-research file. The review was made by hand from the cached publications and PubMed.
Summary with provenance
- ift-20 null (ok3191) worms form only short vestigial cilia PMID:33997658, and they recruit less IFT-74 to the ciliary base and into cilia PMID:33997658.
- IFT-20::GFP undergoes IFT PMID:33997658.
- Unlike mammals, worm IFT-20 is not seen at the Golgi PMID:33997658. Mammalian IFT20 is at the Golgi, the basal body and cilia PMID:16775004.
- Null worms are defective in osmotic avoidance and mating PMID:33997658.
Curation decisions
- 16 GOA rows: 12 ACCEPT, 3 KEEP_AS_NON_CORE (cytoplasm IBA, dendrite IDA, neuronal cell body IDA), and 1 MARK_AS_OVER_ANNOTATED (centrosome IBA). The centrosome row reflects the mammalian context: worm IFT-20 is found only in postmitotic ciliated neurons.
- PMID:33997658 (microPublication 2021) was fetched and added. It has no GOA rows yet. An IMP to non-motile cilium assembly could be added from it, but cilium assembly (IBA) already covers this, so no NEW row was added.