HSPA4: human–horse sequence comparison

The downloaded human P34932 sequence (840 residues) and selected horse A0A9L0S5Z5 sequence (800 residues) share 97.0% identity among 800 paired residues. Paired coverage is 95.2% of human and 100.0% of horse.

Full alignment, hashes, parameters and reproducible script: HSPA4.json and compare.py.

Pairwise similarity supports homology but does not establish reciprocal orthology, intact gene models, conservation of targeting signals or every biological claim. Current UniProt sequences are compared; identity with the original ProtNLM input sequence is unverified.

Architecture check

The selected horse sequence lacks human residues 679–718 internally. Its N-terminal ATPase region is retained; ribosome-associated-complex membership is not established by general Hsp70-family homology.