folP (PA4750, Q9HV49) review notes

No deep-research provider was available; notes compiled from the UniProt entry (unreviewed) and the cached abstract.

DHPS family (TIGR01496, PROSITE PS00792/PS00793, pterin-binding domain). No P. aeruginosa-specific biochemical paper on PA4750 was found in the cache.
PseudoCAP seed reference: PMID:1657875. The paper is about E. coli HPPK and DHPS.

PseudoCAP IBA-seed assessment

PTN node	node term	n_seeds	leaf IBAs	seed annotation (term, evidence, PMID)	other seeds	IBD stands without this seed?	verdict	rationale
PTN000468650	GO:0004156 dihydropteroate synthase activity	6	118 (98 taxa)	GO:0004156, IDA, PMID:1657875 (PseudoCAP)	E. coli FolP P0AC13, S. pneumoniae SulA P59655, M. tuberculosis FolP1 P9WND1, yeast FOL1 (SGD:S000005200), Arabidopsis AT1G69190	Yes	WRONG	The cited paper purified DHPS from E. coli MC4100 (stated in the abstract); no P. aeruginosa protein. The claim is still true for PA4750 by family conservation. Node term suits a DHPS clade.

Defects: PSEUDOCAP WRONG_REFERENCE (CONFIRMED, abstract names E. coli). No GO_CENTRAL defect. Actions: 6 ACCEPT, 2 TOO_GENERAL.