Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara.
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods.
Crystal structure of a heparin- and integrin-binding segment of human fibronectin.
The PE-PGRS glycine-rich proteins of Mycobacterium tuberculosis: a new family of fibronectin-binding proteins?
The fibronectin-binding MSCRAMM FnbpA of Staphylococcus aureus is a bifunctional protein that also binds to fibrinogen.
Binding of a peptide from a Streptococcus dysgalactiae MSCRAMM to the N-terminal F1 module pair of human fibronectin involves both modules.
In vitro localization of TIGR/MYOC in trabecular meshwork extracellular matrix and binding to fibronectin.
Fibulin-1 suppression of fibronectin-regulated cell adhesion and motility.
The type XIII collagen ectodomain is a 150-nm rod and capable of binding to fibronectin, nidogen-2, perlecan, and heparin.
Several regions of the repeat domain of the Staphylococcus caprae autolysin, AtlC, are involved in fibronectin binding.
Matrix-matrix interaction of cartilage oligomeric matrix protein and fibronectin.
Elongation factor Tu and E1 beta subunit of pyruvate dehydrogenase complex act as fibronectin binding proteins in Mycoplasma pneumoniae.
Pathogenic bacteria attach to human fibronectin through a tandem beta-zipper.
Fibulin binds to itself and to the carboxyl-terminal heparin-binding region of fibronectin.
The three-dimensional structure of the tenth type III module of fibronectin: an insight into RGD-mediated interactions.
The human plasma proteome: a nonredundant list developed by combination of four separate sources.
Molecular structure and interaction of recombinant human type XVI collagen.
BBK32, a fibronectin binding MSCRAMM from Borrelia burgdorferi, contains a disordered region that undergoes a conformational change on ligand binding.
Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46.
Sequential deposition of latent TGF-beta binding proteins (LTBPs) during formation of the extracellular matrix in human lung fibroblasts.
Laminin-10 and Lutheran blood group glycoproteins in adhesion of human endothelial cells.
Plasminogen activator inhibitor-1 deposition in the extracellular matrix of cultured human mesangial cells.
A novel role for fibronectin type I domain in the regulation of human hematopoietic cell adhesiveness through binding to follistatin domains of FLRG and follistatin.
CT domain of CCN2/CTGF directly interacts with fibronectin and enhances cell adhesion of chondrocytes through integrin alpha5beta1.
Mycobacterium tuberculosis malate synthase is a laminin-binding adhesin.
Interaction of the small proteoglycan decorin with fibronectin. Involvement of the sequence NKISK of the core protein.
Identification of novel bacterial plasminogen-binding proteins in the human pathogen Mycobacterium tuberculosis.
Force-induced unfolding of fibronectin in the extracellular matrix of living cells.
TSG-6 binds via its CUB_C domain to the cell-binding domain of fibronectin and increases fibronectin matrix assembly.
Novel adhesin from Pasteurella multocida that binds to the integrin-binding fibronectin FnIII9-10 repeats.
Uteroglobin interacts with the heparin-binding site of fibronectin and prevents fibronectin-IgA complex formation found in IgA-nephropathy.
NEDD8 acts as a 'molecular switch' defining the functional selectivity of VHL.
The surface-exposed carboxyl region of Mycoplasma pneumoniae elongation factor Tu interacts with fibronectin.
Crystal structures of fibronectin-binding sites from Staphylococcus aureus FnBPA in complex with fibronectin domains.
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Spontaneous phosphoinositide 3-kinase signaling dynamics drive spreading and random migration of fibroblasts.
Surface displaced alfa-enolase of Lactobacillus plantarum is a fibronectin binding protein.
Enolase from Paracoccidioides brasiliensis: isolation and identification as a fibronectin-binding protein.
The first draft of the endostatin interaction network.
Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.
Fibronectin forms the most extensible biological fibers displaying switchable force-exposed cryptic binding sites.
The interaction of angiocidin with tissue transglutaminase.
EGF potentiated oncogenesis requires a tissue transglutaminase-dependent signaling pathway leading to Src activation.
Lipid phosphate phosphatase 3 stabilization of beta-catenin induces endothelial cell migration and formation of branching point structures.
Zinc induces structural reorganization of gelatin binding domain from human fibronectin and affects collagen binding.
Proteomics characterization of extracellular space components in the human aorta.
Functional analysis of a murine monoclonal antibody against the repetitive region of the fibronectin-binding adhesins fibronectin-binding protein A and fibronectin-binding protein B from Staphylococcus aureus.
Repeat regions R1 and R2 in the P97 paralogue Mhp271 of Mycoplasma hyopneumoniae bind heparin, fibronectin and porcine cilia.
Morphologic and proteomic characterization of exosomes released by cultured extravillous trophoblast cells.
The A domain of fibronectin-binding protein B of Staphylococcus aureus contains a novel fibronectin binding site.
Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.
Transglutaminase-2 interaction with heparin: identification of a heparin binding site that regulates cell adhesion to fibronectin-transglutaminase-2 matrix.
Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability.
Cleavage of nidogen-1 by cathepsin S impairs its binding to basement membrane partners.
Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.
SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers.
Identification and comparative analysis of hepatitis C virus-host cell protein interactions.
SERPINA5 inhibits tumor cell migration by modulating the fibronectin-integrin β1 signaling pathway in hepatocellular carcinoma.
Structural basis for pure antagonism of integrin αVβ3 by a high-affinity form of fibronectin.
Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.
Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.
Structural and functional analysis of the fibronectin-binding protein FNE from Streptococcus equi spp. equi.
Proteolytic processing of the cilium adhesin MHJ_0194 (P123J ) in Mycoplasma hyopneumoniae generates a functionally diverse array of cleavage fragments that bind multiple host molecules.
Lipoprotein(a) binds to fibronectin and has serine proteinase activity capable of cleaving it.
A proteome-scale map of the human interactome network.
Fibulin1C peptide induces cell attachment and extracellular matrix deposition in lung fibroblasts.
A collagen VI-dependent pathogenic mechanism for Hirschsprung's disease.
Extracellular Fibrinogen-binding Protein (Efb) from Staphylococcus aureus Inhibits the Formation of Platelet-Leukocyte Complexes.
Mapping and Exploring the Collagen-I Proteostasis Network.
Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.
Mycobacterial antigen 85 complex (Ag85) as a target for ficolins and mannose-binding lectin.
Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.
Interactions of surface-displayed glycolytic enzymes of Mycoplasma pneumoniae with components of the human extracellular matrix.
Comprehensive proteomic characterization of stem cell-derived extracellular matrices.
Proteomic characterization of human multiple myeloma bone marrow extracellular matrix.
Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.
Lubricin binds cartilage proteins, cartilage oligomeric matrix protein, fibronectin and collagen II at the cartilage surface.
Insights into the structure and dynamics of lysyl oxidase propeptide, a flexible protein with numerous partners.
Mapping the collagen-binding site of human fibronectin by expression in Escherichia coli.
Characterization of fibronectin-binding antigens released by Mycobacterium tuberculosis and Mycobacterium bovis BCG.
Scavenger Receptor Cysteine-Rich domains of Lysyl Oxidase-Like2 regulate endothelial ECM and angiogenesis through non-catalytic scaffolding mechanisms.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Structural insights into integrin α(5)β(1) opening by fibronectin ligand.
Blockade of checkpoint ILT3/LILRB4/gp49B binding to fibronectin ameliorates autoimmune disease in BXSB/Yaa mice.
Stabilin-1 mediates beneficial monocyte recruitment and tolerogenic macrophage programming during CVB3-induced viral myocarditis.
Incorporation of thrombospondin into fibrin clots.
Further characterization of the NH2-terminal fibrin-binding site on fibronectin.
Novel interaction of apolipoprotein(a) with beta-2 glycoprotein I mediated by the kringle IV domain.
The self-association and fibronectin-binding sites of fibulin-1 map to calcium-binding epidermal growth factor-like domains.
Fibronectin degradation by MMP1, 3, 7, 12, 13, 19, CTSS
Integrin alpha5beta1 binds FN1 dimer
Integrins alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 bind Fibronectin matrix
FN1 binds Collagen types I-V, VII
HSPG2 binds FGF2(10-155), Fibronectn matrix, Transthyretin tetramer, PDGFA homodimer, PDGFB homodimer
Fibronectin degradation by MMP14
Fibulin-1 and -2 bind fibronectin
Tenascins C, R, (X, N) bind fibronectin matrix
Syndecan-1 binds fibronectin
Interaction of integrin alphaIIbbeta3 with Fibronectin
Translocation of PTK2 to Focal complexes
Autophosphorylation of PTK2 at Y397
Recruitment of GRB2 to p-PTK2
Phosphorylation of pPTK2 by SRC
Interaction of integrin alphaIIb beta3 with Fibrinogen
Interaction of SOS with GRB2 bound to FADK1
Phosphorylation of BCAR1 by SRC-PTK2 complex
Recruitment of BCAR1 to PTK2 complex
Autophosphorylation of SRC
Clustering of Integrin alphaIIb beta3 complexes
Dephosphorylation of inactive SRC by PTPB1
Fibronectin degradation by CTSG
Fibronectin degradation by ADAM8
SYK binds to integrin alphaIIb beta3
Exocytosis of platelet alpha granule contents
Expression of IL4, IL13-upregulated extracellular proteins
FAM20C phosphorylates FAM20C substrates
p-SHC1 binds integrin alpha5beta1:fibronectin
SfaS binds the fibronectin matrix
ALK mutants bind type I TKIs
Ligand-independent dimerization of ALK fusions
Autophosphorylation of ALK fusions
ALK mutants phosphorylate SHC1
PI3K synthesizes PIP3 downstream of ALK mutants
ALK mutants phosphorylate STAT3
ALK mutants:p-3Y SHC binds GRB2
pY-STAT3 dimer translocates to the nucleus downstream of ALK mutants
PP2A dephosphorylates serine-127 of YAP1
CsgA binds the fibronectin matrix
Deep research report for FN1
UniProt record for FN1 (P02751)