SGD gene description for ZWF1 (yeast)
The yeast transcription factor Stb5 acts as a negative regulator of autophagy by modulating cellular metabolism.
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Loss of ZWF1 modestly enhances starvation-induced autophagy, independently of Stb5.
"In the zwf1 ∆ strain, we found that Pho8∆60-dependent phosphatase activity was enhanced (>15%) relative to WT under starvation conditions, suggesting that Zwf1 functions as a negative modulator of autophagy"
Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniPathway vocabulary mapping
Combined Automated Annotation using Multiple IEA Methods
YeastPathways to GO-CAM conversion
Subcellular localization of the yeast proteome.
Global analysis of protein localization in budding yeast.
Identification of the structural gene for glucose-6-phosphate dehydrogenase in yeast. Inactivation leads to a nutritional requirement for organic sulfur.
Isolation and characterization of the ZWF1 gene of Saccharomyces cerevisiae, encoding glucose-6-phosphate dehydrogenase.
Pentose phosphate pathway mutants of yeast.
Mutants of Saccharomyces cerevisiae sensitive to oxidative and osmotic stress.
Pentose-phosphate pathway in Saccharomyces cerevisiae: analysis of deletion mutants for transketolase, transaldolase, and glucose 6-phosphate dehydrogenase.
Importance of glucose-6-phosphate dehydrogenase in the adaptive response to hydrogen peroxide in Saccharomyces cerevisiae.
UniProt entry P11412 (ZWF1)