GO_REF:0000044

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

GO_REF:0000044 supplied the plasma membrane GOA annotation reviewed in this file.

file:POPTR/CASPL4C2/CASPL4C2-uniprot.txt

UniProtKB reviewed entry for CASPL4C2

UniProt identifies CASPL4C2 as a CASP-like protein of the Casparian strip membrane proteins family, a multi-pass cell membrane protein.

file:POPTR/CASPL4C2/CASPL4C2-goa.tsv

QuickGO GOA annotations for CASPL4C2

GOA supplied the plasma membrane annotation reviewed in this file.

PMID:24920445

Functional and evolutionary analysis of the CASPARIAN STRIP MEMBRANE DOMAIN PROTEIN family.

Defines the CASP/CASPL family and distinguishes the divergent, largely uncharacterized CASP-like subfamily from the bona fide Casparian strip CASP proteins.

PMID:26399665

A Casparian strip domain-like gene, CASPL, negatively alters growth and cold tolerance.

The CASPL4C1 ortholog (Arabidopsis AtCASPL4C1; watermelon ClCASPL), in the same subfamily as this poplar protein, localizes to the plasma membrane, is cold-inducible and broadly expressed, and negatively regulates growth, biomass and flowering time while modulating cold tolerance, acting beyond root Casparian strip formation.

file:projects/CASPL_FAMILY/bioinformatics/expression/RESULTS.md

Poplar CASPL expression analysis (EBI Expression Atlas) - RESULTS

PtCASPL4C2 is phloem-enriched and salt/heat-induced, consistent with a stress-associated CASPL4C-clade role.