Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Involvement of an active efflux system in the natural resistance of Pseudomonas aeruginosa to aminoglycosides.
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MexXY is an energy-dependent efflux system for aminoglycosides that works with OprM.
"Antibiotic accumulation studies confirmed that this new system is an energy-dependent active efflux system that pumps out aminoglycosides."
Contribution of the MexX-MexY-oprM efflux system to intrinsic resistance in Pseudomonas aeruginosa.
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Isogenic mexXY deletion increases antibiotic susceptibility; MexX is induced by antibiotics.
"Loss of either MexXY or OprM from the MexAB-deficient mutant increased susceptibility to all agents tested"
Substrate specificities of MexAB-OprM, MexCD-OprJ, and MexXY-oprM efflux pumps in Pseudomonas aeruginosa.
Role of the membrane fusion protein in the assembly of resistance-nodulation-cell division multidrug efflux pump in Pseudomonas aeruginosa.
Induction of the MexXY efflux pump in Pseudomonas aeruginosa is dependent on drug-ribosome interaction.
Mutational analysis of the OprM outer membrane component of the MexA-MexB-OprM multidrug efflux system of Pseudomonas aeruginosa.
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MFPs of P. aeruginosa RND pumps, including MexX, are cytoplasmic-membrane-anchored periplasmic proteins.
"a periplasmic but cytoplasmic membrane-anchored membrane fusion protein ( 15 ) (MexA, MexC, MexE, and MexX)"