Annotation inferences using phylogenetic trees
Genetic and biochemical analyses of the Pseudomonas aeruginosa Psl exopolysaccharide reveal overlapping roles for polysaccharide synthesis enzymes in Psl and LPS production.
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In-frame deletion of pslC (one of 11 psl genes) abolishes Psl production and surface attachment; Psl is a Man/Glc/Rha pentasaccharide repeat.
"In this study we have demonstrated that eleven of the fifteen psl genes, pslACDEFGHIJKL, are required for Psl synthesis and solid surface attachment."
Biosynthesis of the Pseudomonas aeruginosa Extracellular Polysaccharides, Alginate, Pel, and Psl.
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PslC is predicted to be a soluble GT-2 glycosyltransferase of unknown sugar specificity.
"Enzymes in the GT-2 family transfer a wide variety of nucleotide activated sugars (including glucose, rhamnose, and mannose), so it is difficult to speculate which of these substrates PslC specifically recognizes."