Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniPathway vocabulary mapping
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Combined Automated Annotation using Multiple IEA Methods
Characterization of Arabidopsis FPS isozymes and FPS gene expression analysis provide insight into the biosynthesis of isoprenoid precursors in seeds.
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Purified recombinant FPS1S shows Michaelis-Menten kinetics with IPP, DMAPP and GPP (Km 8.3-31.5 uM)
"Both enzymes displayed typical Michaelis-Menten behaviour, as observed for other FPSs, and exhibited similar K m values in the µmolar range (from 8.3 to 31.5 µM) for both IPP and the allylic substrates DMAPP and GPP."
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GFP fusions of FPS1S localize exclusively to the cytosol
"Under our experimental conditions all the four fusion proteins localized exclusively in the cytosol (Figure 5)."
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FPS1S expressed from the FPS2 promoter rescues fps2 seed phenotypes
"Altogether, these results demonstrated that FPS1S is able to functionally replace FPS2."
A proteomic strategy for global analysis of plant protein complexes.
Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling.
The Arabidopsis thaliana FPS1 gene generates a novel mRNA that encodes a mitochondrial farnesyl-diphosphate synthase isoform.
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FPS1L N-terminal extension is a functional mitochondrial transit peptide
"The functionality of the FPS1L NH2-terminal extension as a mitochondrial transit peptide was demonstrated by its ability to direct a passenger protein to yeast mitochondria in vivo and by in vitro import experiments using purified plant mitochondria."
The Arabidopsis thaliana FPP synthase isozymes have overlapping and specific functions in isoprenoid biosynthesis, and complete loss of FPP synthase activity causes early developmental arrest.
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FPS1 provides the predominant FPS activity during most of the life cycle; fps1 fps2 double knockout is embryo lethal
"FPS1 activity has a predominant role during most of the plant life cycle, and FPS2 appears to have a major role in seeds and during the early stages of seedling development."
Arabidopsis thaliana contains two differentially expressed farnesyl-diphosphate synthase genes.
Suppressing Farnesyl Diphosphate Synthase Alters Chloroplast Development and Triggers Sterol-Dependent Induction of Jasmonate- and Fe-Related Responses.
UniProt entry Q09152 (FPPS1_ARATH)
Manual literature research for FPS1