GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
GO_REF:0000107
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
GO_REF:0000119
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
GO_REF:0000120
Combined Automated Annotation using Multiple IEA Methods
PMID:25594178
A kinase-independent role for EGF receptor in autophagy initiation.
PMID:19270693
Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex.
PMID:20974968
Rubicon controls endosome maturation as a Rab7 effector.
PMID:20943950
Rubicon and PLEKHM1 negatively regulate the endocytic/autophagic pathway via a novel Rab7-binding domain.
PMID:21062745
The RUN domain of rubicon is important for hVps34 binding, lipid kinase inhibition, and autophagy suppression.
PMID:32632011
Structural basis for autophagy inhibition by the human Rubicon-Rab7 complex.
PMID:30783089
Suppression of autophagic activity by Rubicon is a signature of aging.
PMID:27637015
Rubicon inhibits autophagy and accelerates hepatocyte apoptosis and lipid accumulation in nonalcoholic fatty liver disease in mice.
PMID:35282767
Loss of RUBCN/rubicon in adipocytes mediates the upregulation of autophagy to promote the fasting response.
PMID:28306502
Pacer Mediates the Function of Class III PI3K and HOPS Complexes in Autophagosome Maturation by Engaging Stx17.
PMID:22423966
Autophagy protein Rubicon mediates phagocytic NADPH oxidase activation in response to microbial infection or TLR stimulation.
PMID:22423967
The autophagy regulator Rubicon is a feedback inhibitor of CARD9-mediated host innate immunity.
file:mouse/Rubcn/Rubcn-uniprot.txt
UniProtKB record for mouse Rubcn (Q80U62)
file:mouse/Rubcn/Rubcn-notes.md
Rubcn review notes