Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Gene Ontology annotation based on curation of immunofluorescence data

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

Unique properties of lamp2a compared to other lamp2 isoforms.

Identification of a novel domain in two mammalian inositol-polyphosphate 5-phosphatases that mediates membrane ruffle localization. The inositol 5-phosphatase skip localizes to the endoplasmic reticulum and translocates to membrane ruffles following epidermal growth factor stimulation.

Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment.

The nucleotide transporter MRP4 (ABCC4) is highly expressed in human platelets and present in dense granules, indicating a role in mediator storage.

Exosomal-like vesicles are present in human blood plasma.

Integral and associated lysosomal membrane proteins.

The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane.

Large-scale proteomics and phosphoproteomics of urinary exosomes.

Printor, a novel torsinA-interacting protein implicated in dystonia pathogenesis.

Chaperone-mediated autophagy: molecular mechanisms and physiological relevance.

The lysosomal polypeptide transporter TAPL: more than a housekeeping factor?

Signal-peptide-peptidase-like 2a (SPPL2a) is targeted to lysosomes/late endosomes by a tyrosine motif in its C-terminal tail.

The lysosomal polypeptide transporter TAPL is stabilized by interaction with LAMP-1 and LAMP-2.

Regulation of ATG4B stability by RNF5 limits basal levels of autophagy and influences susceptibility to bacterial infection.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

Degradation of AF1Q by chaperone-mediated autophagy.

Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo.

Human neutrophils secrete bioactive paucimannosidic proteins from azurophilic granules into pathogen-infected sputum.

Chaperone-mediated autophagy prevents apoptosis by degrading BBC3/PUMA.

LAMP-2 is required for incorporating syntaxin-17 into autophagosomes and for their fusion with lysosomes.

The lysosomal protein cathepsin L is a progranulin protease.

Purification and characterization of human lysosomal membrane glycoproteins.

Deficiency of cancer/testis antigen gene CT55 causes male infertility in humans and mice.

Palmitoylation prevents sustained inflammation by limiting NLRP3 inflammasome activation through chaperone-mediated autophagy.

Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel.

ABHD8 antagonizes inflammation by facilitating chaperone-mediated autophagy-mediated degradation of NLRP3.

PSAT1 impairs ferroptosis and reduces immunotherapy efficacy via GPX4 hydroxylation.

Surface deployment of platelet dense granule membrane components

Exocytosis of azurophil granule membrane proteins

Exocytosis of ficolin-rich granule membrane proteins

UniProt record P13473 (LAMP2)