Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Combined Automated Annotation using Multiple IEA Methods
Carbamate kinase from Pseudomonas aeruginosa: purification, characterization, physiological role, and regulation.
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Carbamate kinase was purified from PAO1 and is distinct from carbamoyl-phosphate synthetase and acetate kinase.
"Pseudomonas aeruginosa PAO1 possessed a carbamate kinase (CKase) distinct from carbamoylphosphate synthetase as well as from a constitutive acetate kinase which also catalyzes the phosphorylation of ADP by carbamoylphosphate"
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Expression is induced by anaerobiosis and arginine; the enzyme supplies ATP anaerobically and ammonia aerobically.
"CKase expression is regulated in a manner that allows the enzyme to function as a provider of ammonia under aerobic conditions and of ATP under anaerobic conditions"
Pseudomonas aeruginosa mutants affected in anaerobic growth on arginine: evidence for a four-gene cluster encoding the arginine deiminase pathway.
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arcC mutants lack carbamate kinase and are blocked in anaerobic arginine catabolism.
"The mutations arcA (arginine deiminase), arcB (catabolic ornithine carbamoyltransferase), arcC (carbamate kinase), and arcD were highly cotransducible"
arcC (PA5173) review notes