rps-23 notes
- 2026-10-28: fetched Q19877 (RS23_CAEEL; GeneID 178188, WBGene00004492); accession confirmed.
- GOA: 15 rows, all IBA/IEA/ISS; no experimental rows.
- Literature: PMID:39209556 (C. elegans 80S cryo-EM, uS12 modelled
PMID:39209556);
PMID:30799226, PMID:41047111, PMID:39786340 (rps-23 null/heterozygote phenotypes from the Sarinay Cenik lab);
PMID:16247027 (RNAi control, sterility). See rps-23-deep-research-manual.md.
- Decisions: ACCEPT structural constituent of ribosome, cytosolic small ribosomal subunit, cytoplasmic translation,
cytosol; MODIFY general rows (ribosome, small ribosomal subunit, translation, cytoplasm) to their specific
descendants; rough ER kept as non-core (membrane-bound ribosomes; orthology only).
- No NEW terms: phenotypes (L1 arrest, mitochondrial morphology, lifespan) are indirect, necessity-only evidence.
- uS12's decoding-centre role (translational fidelity) is plausible by homology but has no worm data; recorded as a
question rather than a NEW annotation.