Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt.
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara.
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods.
Ca(2+)-dependent and Ca(2+)-independent calmodulin binding sites in erythrocyte protein 4.1. Implications for regulation of protein 4.1 interactions with transmembrane proteins.
Calmodulin regulation of basal and agonist-stimulated G protein coupling by the mu-opioid receptor (OP(3)) in morphine-pretreated cell.
Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin.
Requirement of Ca2+ and CaMKII for Stat1 Ser-727 phosphorylation in response to IFN-gamma.
The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins.
Comparative analyses of the three-dimensional structures and enzymatic properties of alpha, beta, gamma and delta isoforms of Ca2+-calmodulin-dependent protein kinase II.
Ca2+-binding protein-1 facilitates and forms a postsynaptic complex with Cav1.2 (L-type) Ca2+ channels.
Myristoyl moiety of HIV Nef is involved in regulation of the interaction with calmodulin in vivo.
Calcium/calmodulin regulates ubiquitination of the ubiquitin-specific protease TRE17/USP6.
CP110 cooperates with two calcium-binding proteins to regulate cytokinesis and genome stability.
Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense.
Structural analysis of the complex between calmodulin and full-length myelin basic protein, an intrinsically disordered molecule.
Defective calmodulin binding to the cardiac ryanodine receptor plays a key role in CPVT-associated channel dysfunction.
Structure of the CaMKIIdelta/calmodulin complex reveals the molecular mechanism of CaMKII kinase activation.
Solution NMR structure of Apo-calmodulin in complex with the IQ motif of human cardiac sodium channel NaV1.5.
IQ-motif selectivity in human IQGAP2 and IQGAP3: binding of calmodulin and myosin essential light chain.
Proteomic characterization of the human sperm nucleus.
FRET detection of calmodulin binding to the cardiac RyR2 calcium release channel.
Quantitative proteomic analysis of human substantia nigra in Alzheimer's disease, Huntington's disease and Multiple sclerosis.
Mutations in calmodulin cause ventricular tachycardia and sudden cardiac death.
Distinctive malfunctions of calmodulin mutations associated with heart RyR2-mediated arrhythmic disease.
Spectrum and Prevalence of CALM1-, CALM2-, and CALM3-Encoded Calmodulin Variants in Long QT Syndrome and Functional Characterization of a Novel Long QT Syndrome-Associated Calmodulin Missense Variant, E141G.
Arrhythmogenic calmodulin mutations impede activation of small-conductance calcium-activated potassium current.
Novel CPVT-Associated Calmodulin Mutation in CALM3 (CALM3-A103V) Activates Arrhythmogenic Ca Waves and Sparks.
Structural Insights into the M-Channel Proximal C-Terminus/Calmodulin Complex.
The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation.
Regulation of KIF1A-Driven Dense Core Vesicle Transport: Ca(2+)/CaM Controls DCV Binding and Liprin-α/TANC2 Recruits DCVs to Postsynaptic Sites.
Calcineurin B homologous protein 3 binds with high affinity to the CHP binding domain of the human sodium/proton exchanger NHE1.
An IQSEC2 Mutation Associated With Intellectual Disability and Autism Results in Decreased Surface AMPA Receptors.
Comparison of S100b protein with calmodulin: interactions with melittin and microtubule-associated tau proteins and inhibition of phosphorylation of tau proteins by protein kinase C.
Genetic Mosaicism in Calmodulinopathy.
Interaction between IDH1 WT and calmodulin and its implications for glioblastoma cell growth and migration.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling.
A calmodulin-binding sequence in the C-terminus of human cardiac titin kinase.
Blocking the Ca2+-induced conformational transitions in calmodulin with disulfide bonds.
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle
BH2 binding can lead to eNOS uncoupling
Uncoupled eNOS favours the formation of superoxide
I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol
eNOS:Caveolin-1 complex binds to CaM
HSP90 binds eNOS:Caveolin-1:CaM complex
AKT1 binds eNOS complex via HSP90
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex
Calcineurin binds NFATC1,2,3
Calcineurin binds and dephosphorylates NFAT
Translocation of CaN:CaM:NFAT to nucleus
Activation of Calcineurin
CALM1:Ca2+ binds CNG channel
Dissociation of CaM and CAMK2 autophosphorylation
Active calmodulin binds CAMK2
Autophosphorylation and activation of CAMK2
CaMKK autophosphorylates in the nucleus
MYLK (MLCK) Active Calmodulin Binding
Phosphorylation of Smooth Muscle Myosin Light Chains
kainate receptor binds glutamate
Activation of Ca-permeable Kainate receptors
Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling
Translocation of NFATC1:CaN:CaM to nucleus
Release of platelet cytosolic components
RAS GEFs promote RAS nucleotide exchange
KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1
glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP
glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP
Calmodulin binds neurogranin
CaMKK autophosphorylates in the cytosol
S-Farn-Me KRAS4B binds calmodulin
Calmodulin dissociates KRAS4B from the plasma membrane
ARL2:GTP bind PDE6D on KRAS4B
PDE6D binds S-Farn-Me KRAS4B:CALM:4 Ca2+
KRAS4B recycles to the plasma membrane
TRPV4 tetramer binds CALM1:Ca2+ (calmodulin:Ca2+)
Rasgrf1 promotes activation of HRAS
Camkk1 binds activated calmodulin in the nucleus
Camkk2 phosphorylates CAMK4
Camkk1 binds activated calmodulin in the cytosol
CAMKK1 phosphorylates CAMK1
CAMKK2 phosphorylates Camk1
Deep research on CALM1 function