GO_REF:0000002

Gene Ontology annotation through association of InterPro records with GO terms

GO_REF:0000117

Electronic Gene Ontology annotations created by ARBA machine learning models

GO_REF:0000118

TreeGrafter-generated GO annotations

GO_REF:0000120

Combined Automated Annotation using Multiple IEA Methods

file:PSEPK/lpd/lpd-uniprot.txt

UniProt record for lpd (Q88C17)

UniProt identifies lpd as Dihydrolipoyl dehydrogenase (EC 1.8.1.4) and provides the seeded EC/domain/GO evidence reviewed here.

file:PSEPK/lpd/lpd-deep-research-asta.md

Asta deep-research retrieval for lpd

Asta retrieval was run for this first-pass pathway curation; direct organism-specific literature was limited for several common enzyme names, so UniProt/family evidence carries the main review weight.

file:PSEPK/lpd/lpd-deep-research-openscientist.md

OpenScientist deep research report for lpd

The report supports the exact E3 chemistry while leaving the physiological client complex unresolved.

PMID:1902462

Cloning and sequence analysis of the LPD-glc structural gene of Pseudomonas putida.

The P. putida three-paralog scheme distinguishes LPD-3 as an isozyme of unknown physiological role.

"LPD-3, which was discovered in a lpdG mutant and whose role is unknown."

file:projects/P_PUTIDA/batches/ppu00260_glycine_cleavage_system.md

PSEPK glycine cleavage system batch

Lpd is not selected as the physiological GCS L protein; its role remains unresolved.