Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic Gene Ontology annotation based on Rhea mapping
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
G1-phase and B-type cyclins exclude the DNA-replication factor Mcm4 from the nucleus.
Clb/Cdc28 kinases promote nuclear export of the replication initiator proteins Mcm2-7.
Uninterrupted MCM2-7 function required for DNA replication fork progression.
The B2 element of the Saccharomyces cerevisiae ARS1 origin of replication requires specific sequences to facilitate pre-RC formation.
Reconstitution of the Mcm2-7p heterohexamer, subunit arrangement, and ATP site architecture.
Mcm4,6,7 uses a "pump in ring" mechanism to unwind DNA by steric exclusion and actively translocate along a duplex.
The Mcm467 complex of Saccharomyces cerevisiae is preferentially activated by autonomously replicating DNA sequences.
Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork.
Reconstitution of Saccharomyces cerevisiae prereplicative complex assembly in vitro.
Differences in the single-stranded DNA binding activities of MCM2-7 and MCM467: MCM2 and MCM5 define a slow ATP-dependent step.
The Mcm2-7 complex has in vitro helicase activity.
High-quality binary protein interaction map of the yeast interactome network.
Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing.
A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication.
SCF(Dia2) regulates DNA replication forks during S-phase in budding yeast.
A group of interacting yeast DNA replication genes.
The Saccharomyces cerevisiae Mcm6/2 and Mcm5/3 ATPase active sites contribute to the function of the putative Mcm2-7 'gate'.
Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly.
Mcm10 associates with the loaded DNA helicase at replication origins and defines a novel step in its activation.
Cryo-EM structure of a helicase loading intermediate containing ORC-Cdc6-Cdt1-MCM2-7 bound to DNA.
A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome.
CMG helicase and DNA polymerase ε form a functional 15-subunit holoenzyme for eukaryotic leading-strand DNA replication.
Structure of the eukaryotic MCM complex at 3.8 Å.
The architecture of a eukaryotic replisome.
A new MCM modification cycle regulates DNA replication initiation.
Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation.
The cellular economy of the Saccharomyces cerevisiae zinc proteome.
The social and structural architecture of the yeast protein interactome.
A lesion in the DNA replication initiation factor Mcm10 induces pausing of elongation forks through chromosomal replication origins in Saccharomyces cerevisiae.
Components and dynamics of DNA replication complexes in S. cerevisiae: redistribution of MCM proteins and Cdc45p during S phase.
Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin.
Yeast Mcm2-7 mediated fork unwinding
CDT1 binds MCM2-7 complex in budding yeast
CDT1-mediated loading of MCM2-7 to replication origin in budding yeast
ATP-dependent release of CDT1 from the OCCM complex in budding yeast
CTD1-mediated formation of MCM2-7 double hexamers at the replication origins in budding yeast
UniProtKB/Swiss-Prot entry P30665 (MCM4_YEAST)