Gene Ontology annotation through association of InterPro records with GO terms

Annotation inferences using phylogenetic trees

Automatic Gene Ontology annotation based on Rhea mapping

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

Isolation and characterization of a human thiamine pyrophosphokinase cDNA.

A massively parallel pipeline to clone DNA variants and examine molecular phenotypes of human disease mutations.

An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.

A reference map of the human binary protein interactome.

Pyrimidines maintain mitochondrial pyruvate oxidation to support de novo lipogenesis.

Thiamine pyrophosphokinase deficiency in encephalopathic children with defects in the pyruvate oxidation pathway.

2xTPK1:Mg2+ phosphorylates THMN