Gene Ontology annotation through association of InterPro records with GO terms

Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features

GO_REF:0000120

Combined Automated Annotation using Multiple IEA Methods

file:PSEPK/serS/serS-uniprot.txt

UniProtKB entry for PSEPK serS

HAMAP MF_00176 specifies both tRNA(Ser) and tRNA(Sec) reactions and a homodimer spanning the tRNA-binding surface. Current GO:0004828 explicitly includes the tRNA(Sec) reaction, so no extra MF proposal is required.

"Reaction=tRNA(Ser) + L-serine + ATP = L-seryl-tRNA(Ser) + AMP +"
The curated family rule places the enzyme in the cytoplasm.

"SUBCELLULAR LOCATION: Cytoplasm"
The conserved SerS rule includes serine attachment to tRNA(Sec).

"Reaction=tRNA(Sec) + L-serine + ATP"

file:interpro/panther/PTHR43697/PTHR43697-metadata.yaml

PANTHER family metadata for PTHR43697

The target belongs to the class II serine--tRNA ligase family.

"name: Serine--tRNA ligase, class-II aminoacyl-tRNA synthetase"

file:interpro/panther/PTHR43697/PTHR43697-entries.csv

PANTHER family members for PTHR43697

Q88FT2 is assigned to the serine--tRNA ligase subfamily.

"Q88FT2,Serine--tRNA ligase"