Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Combined Automated Annotation using Multiple IEA Methods
Knockdown of human N alpha-terminal acetyltransferase complex C leads to p53-dependent apoptosis and aberrant human Arl8b localization.
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NatC contains the catalytic subunit hMak3 (NAA30) and auxiliary subunits hMak10 (NAA35) and hMak31 (NAA38); the complex associates with ribosomes.
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Knockdown of NatC subunits results in p53-dependent cell death, indicating NatC normally suppresses apoptosis.
A reference map of the human binary protein interactome.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity.
Multimodal cell maps as a foundation for structural and functional genomics.
Falcon deep research report for NAA35
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NAA35 is the large non-catalytic auxiliary/scaffold subunit of the heterotrimeric NatC complex (with catalytic NAA30 and small auxiliary NAA38); it organizes the complex architecture, contributes to the NAA30-NAA35 substrate-binding interface that determines Met-hydrophobic specificity, and mediates ribosome association via an electropositive C-terminal tip region.