Gene Ontology annotation through association of InterPro records with GO terms

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Automatic assignment of GO terms using logical inference, based on on inter-ontology links

Electronic Gene Ontology annotations created by ARBA machine learning models

TreeGrafter-generated GO annotations

Combined Automated Annotation using Multiple IEA Methods

High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat.

CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance.

Naked mole-rat very-high-molecular-mass hyaluronan exhibits superior cytoprotective properties.

Dysregulation of ADAM10 shedding activity in naked mole-rat fibroblasts is due to deficient phosphatidylserine externalization.

The naked truth: a comprehensive clarification and classification of current 'myths' in naked mole-rat biology.

Evolution of high-molecular-mass hyaluronic acid is associated with subterranean lifestyle.

Abundance and size of hyaluronan in naked mole-rat tissues and plasma.

Naked mole-rat TMEM2 lacks physiological hyaluronan-degrading activity.

Naked mole-rat hyaluronan.

The material properties of naked mole-rat hyaluronan.

Naked mole-rats are extremely resistant to post-traumatic osteoarthritis.

CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex.

Acylation of CD44 and its association with lipid rafts are required for receptor and hyaluronan endocytosis.

CD44-dependent intracellular and extracellular catabolism of hyaluronic acid by hyaluronidase-1 and -2.

Podoplanin associates with CD44 to promote directional cell migration.

Hyaluronidases and CD44 undergo differential modulation during chondrogenesis.

bFGF induces changes in hyaluronan synthase and hyaluronidase isoform expression and modulates the migration capacity of fibrosarcoma cells.

BMP-7 modulates hyaluronan-mediated proximal tubular cell-monocyte interaction.

Proinflammatory cytokines induce hyaluronan synthesis and monocyte adhesion in human endothelial cells through hyaluronan synthase 2 (HAS2) and the nuclear factor-kappaB (NF-kappaB) pathway.

Galectin-9 promotes natural killer cells activity via interaction with CD44.

UniProt entry A0AAX6R0R7 (Cd44, Heterocephalus glaber)

Naked mole-rat Cd44 isoform architecture and hyaluronan-binding site analysis

Affinage mechanistic annotation for CD44 (human ortholog P16070)