TARS2 notes

Literature review was done manually from cached PubMed records; the falcon deep-research report (TARS2-deep-research-falcon.md) completed afterwards and was skimmed for consistency with the review decisions; no conflicts were found.

• Purified human mitochondrial ThrRS: aminoacylation plus post-transfer editing of Ser PMID:26811336.
• Disease variant P282L lowers activation, aminoacylation and proofreading PMID:26811336.
• Patient fibroblasts have reduced charged mt-tRNA(Thr) PMID:24827421.
• Obsolete GO terms threonyl-tRNA aminoacylation (GO:0006435, GO:0070159) are replaced with GO:0070127 tRNA aminoacylation for mitochondrial protein translation.
• The non-canonical Rag GTPase/mTORC1 role modelled in dismech (COXPD21 entry) is not represented in GOA and is left as a suggested question.