Gene Ontology annotation through association of InterPro records with GO terms
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Combined Automated Annotation using Multiple IEA Methods
Functional domain analysis of the Saccharomyces MAL-activator.
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Functional-domain (LexA-fusion deletion) analysis of the Saccharomyces MAL-activator, performed on Mal63p: DNA-binding domain in residues 1-100, a functional core including the transactivation domain in residues 60-283, an inhibitory region in residues 251-299, and a C-terminal maltose-responsive domain that relieves the inhibition, giving a model of maltose-inducible autoregulation.
"Our results indicate that the sequence-specific DNA-binding domain of Mal63p is contained in residues 1-100; that residues 60-283 constitute a functional core region including the transactivation domain; that residues 251-299 are required to inhibit the activation function of Mal63p; and that the rest of the C-terminal region of the protein contains a maltose-responsive domain"
The cellular economy of the Saccharomyces cerevisiae zinc proteome.
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Bioinformatic definition of the S. cerevisiae zinc proteome (582 known or potential zinc-binding proteins) by combined domain and motif searches, within which MAL33 is included as a zinc-binding protein consistent with its Zn2Cys6 domain.
"The yeast zinc proteome of 582 known or potential zinc-binding proteins was identified using a bioinformatics analysis that combined global domain searches with local motif searches."
The telomere-associated MAL3 locus of Saccharomyces is a tandem array of repeated genes.
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The MAL3 locus of S. cerevisiae (chromosome II, telomere-associated) is a tandem array of repeated MAL genes; MAL33 is the MAL-activator gene of this multigene complex, alongside the MAL31 permease and MAL32 maltase genes.