Gene Ontology annotation through association of InterPro records with GO terms

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping

Gene Ontology annotation based on curation of immunofluorescence data

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

Primary structure of the human 4F2 antigen heavy chain predicts a transmembrane protein with a cytoplasmic NH2 terminus.

Molecular cloning of complementary DNAs encoding the heavy chain of the human 4F2 cell-surface antigen: a type II membrane glycoprotein involved in normal and neoplastic cell growth.

Amino-acid transport by heterodimers of 4F2hc/CD98 and members of a permease family

Amino acid transport of y+L-type by heterodimers of 4F2hc/CD98 and members of the glycoprotein-associated amino acid transporter family.

Identification of a membrane protein, LAT-2, that Co-expresses with 4F2 heavy chain, an L-type amino acid transport activity with broad specificity for small and large zwitterionic amino acids.

LAT2, a new basolateral 4F2hc/CD98-associated amino acid transporter of kidney and intestine.

The heterodimeric amino acid transporter 4F2hc/y+LAT2 mediates arginine efflux in exchange with glutamine.

Association of 4F2hc with light chains LAT1, LAT2 or y+LAT2 requires different domains

Identification and characterisation of human xCT that co-expresses, with 4F2 heavy chain, the amino acid transport activity system xc-.

Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines.

Thyroid hormone transport by the heterodimeric human system L amino acid transporter

LAPTM4b recruits the LAT1-4F2hc Leu transporter to lysosomes and promotes mTORC1 activation.

Hepatitis C Virus Modulates Solute carrier family 3 member 2 for Viral Propagation.

Structure of the human LAT1-4F2hc heteromeric amino acid transporter complex

Structural insight into the substrate recognition and transport mechanism of the human LAT2-4F2hc complex.

Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter.

Plasmodium vivax binds host CD98hc (SLC3A2) to enter immature red blood cells.

Molecular basis for redox control by the human cystine/glutamate antiporter system xc

SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate

Cloning and expression of a b(0,+)-like amino acid transporter functioning as a heterodimer with 4F2hc instead of rBAT. A new candidate gene for cystinuria.

Cloning and functional characterization of a Na(+)-independent, broad-specific neutral amino acid transporter from mammalian intestine.

Heterodimeric amino acid transporters: expression of heavy but not light chains of CD98 correlates with induction of amino acid transport systems in human placental trophoblast.

Identification and characterization of a Na(+)-independent neutral amino acid transporter that associates with the 4F2 heavy chain and exhibits substrate selectivity for small neutral D- and L-amino acids.

Characterization of the system L amino acid transporter in T24 human bladder carcinoma cells.

Molecular cloning and characterization of CT120, a novel membrane-associated gene involved in amino acid transport and glutathione metabolism.

Human LAT1 single nucleotide polymorphism N230K does not alter phenylalanine transport.

Identification of stereoselective transporters for S-nitroso-L-cysteine: role of LAT1 and LAT2 in biological activity of S-nitrosothiols.

Ornithine transport via cationic amino acid transporter-1 is involved in ornithine cytotoxicity in retinal pigment epithelial cells.

Large-scale proteomics and phosphoproteomics of urinary exosomes.

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).

Quantitative proteomics identifies a Dab2/integrin module regulating cell migration.

Defining the membrane proteome of NK cells.

The pathogenic E. coli type III effector EspZ interacts with host CD98 and facilitates host cell prosurvival signalling.

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.

Raftlin is involved in the nucleocapture complex to induce poly(I:C)-mediated TLR3 activation.

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.

Quantitative targeted absolute proteomic analysis of transporters, receptors and junction proteins for validation of human cerebral microvascular endothelial cell line hCMEC/D3 as a human blood-brain barrier model.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

KSHV attachment and entry are dependent on αVβ3 integrin localized to specific cell surface microdomains and do not correlate with the presence of heparan sulfate.

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

Impaired Amino Acid Transport at the Blood Brain Barrier Is a Cause of Autism Spectrum Disorder.

LC-MS/MS Based Quantitation of ABC and SLC Transporter Proteins in Plasma Membranes of Cultured Primary Human Retinal Pigment Epithelium Cells and Immortalized ARPE19 Cell Line.

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.

Quantitative Protein Expression in the Human Retinal Pigment Epithelium: Comparison Between Apical and Basolateral Plasma Membranes With Emphasis on Transporters.

OpenCell: Endogenous tagging for the cartography of human cellular organization.

The solute carrier superfamily interactome.

SLC7A8-mediated uptake of neutral amino acids

SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol

Basigin binds CD98 complex

SLC7A10-mediated uptake of small neutral amino acids

SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane

SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine

Defective SLC7A7 does not exchange L-Arg for L-Leu, Na+ across the plasma membrane

Deep research report on SLC3A2