Gene Ontology annotation through association of InterPro records with GO terms

Gene Ontology annotation based on Enzyme Commission mapping

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Electronic Gene Ontology annotations created by ARBA machine learning models

Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs

Combined Automated Annotation using Multiple IEA Methods

The negative regulator of Gli, Suppressor of fused (Sufu), interacts with SAP18, Galectin3 and other nuclear proteins.

Transcriptional activity of peroxisome proliferator-activated receptor gamma is modulated by SUMO-1 modification.

Control of peroxisome proliferator-activated receptor gamma2 stability and activity by SUMOylation.

The transactivating function of peroxisome proliferator-activated receptor gamma is negatively regulated by SUMO conjugation in the amino-terminal domain.

A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma.

Interaction of protein inhibitor of activated STAT (PIAS) proteins with the TATA-binding protein, TBP.

PIAS1 confers DNA-binding specificity on the Msx1 homeoprotein.

The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through NFkappaB.

SUMOylation of Tr2 orphan receptor involves Pml and fine-tunes Oct4 expression in stem cells.

Sumoylation of peroxisome proliferator-activated receptor gamma by apoptotic cells prevents lipopolysaccharide-induced NCoR removal from kappaB binding sites mediating transrepression of proinflammatory cytokines.

The SUMO E3-ligase PIAS1 regulates the tumor suppressor PML and its oncogenic counterpart PML-RARA.

PIAS1 is a GATA4 SUMO ligase that regulates GATA4-dependent intestinal promoters independent of SUMO ligase activity and GATA4 sumoylation.

Forkhead box protein A2 (FOXA2) protein stability and activity are regulated by sumoylation.

Protein inhibitor of activated STAT 1 (PIAS1) is identified as the SUMO E3 ligase of CCAAT/enhancer-binding protein β (C/EBPβ) during adipogenesis.

Super-resolution study of PIAS SUMO E3-ligases in hippocampal and cortical neurons.

Inhibition of Stat1-mediated gene activation by PIAS1.

Pias1 Sumoylates Nr2c1 (Tr2)

Pias1,2-2 Sumoylate Pparg with Sumo1

PIAS1 selectively inhibits interferon-inducible genes and is important in innate immunity.

Negative regulation of NF-kappaB signaling by PIAS1.

SUMO modification of STAT1 and its role in PIAS-mediated inhibition of gene activation.

Proinflammatory stimuli induce IKKalpha-mediated phosphorylation of PIAS1 to restrict inflammation and immunity.

Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks.

Crosstalk between SUMOylation and ubiquitylation controls DNA end resection by maintaining MRE11 homeostasis on chromatin.

SUMO Ligase Protein Inhibitor of Activated STAT1 (PIAS1) Is a Constituent Promyelocytic Leukemia Nuclear Body Protein That Contributes to the Intrinsic Antiviral Immune Response to Herpes Simplex Virus 1.

UniProt entry for mouse Pias1 (O88907)

OpenScientist deep research report for Pias1 (mouse)