trpI (PA0037, P11720) notes

No deep-research provider was available. Literature: PMID:1904858 and PMID:2107533 (abstracts only;
no PMC body available).

Biology

In vitro transcription with purified TrpI PMID:1904858; direct effect PMID:1904858.
Binding sites PMID:2107533.
No GO term for regulation of tryptophan biosynthesis; GO:2000284 is the most specific available.
Related reviews in this folder: trpC, trpE, trpG (biosynthetic enzymes).

Annotation decisions

GO:0003700 (IBA, IEA), GO:0006355 (IBA, IDA, IEA), GO:2000284 (IMP): ACCEPT.
GO:0032993 protein-DNA complex (IPI, CollecTF): KEEP_AS_NON_CORE.
GO:0043565 (IPI, CollecTF): MODIFY to GO:0000976 transcription cis-regulatory region binding.
The GOA file lists the CollecTF IPI rows twice; the review stub holds one row per distinct annotation.
Action counts: ACCEPT 6, KEEP_AS_NON_CORE 1, MODIFY 1.

PseudoCAP IBA-seed assessment

Node-level record for PTN000794521 (shared with ampR, PA4109) is kept here, trpI having the most
direct seed evidence (purified in vitro transcription).

PTN node	node term	n_seeds	leaf IBAs	seed annotation (term, evidence, PMID)	verdict	rationale	other seeds	IBD stands without this seed?
PTN000794521	GO:0006355 regulation of DNA-templated transcription	6	174 (18 taxa)	GO:0006355, IDA, PMID:1904858 (PseudoCAP)	SOUND	Abstract: purified TrpI + InGP activates trpBA and represses trpI transcription in vitro (CONFIRMED-level fact).	ampR P24734 (SOUND term; evidence code should be IMP, see ampR), E. coli GcvA P0A9F6, TtdR P45463, DmlR P76250, PgrR P77333	Yes; four E. coli LysR regulators plus ampR, and the undirected regulation term suits a LysR clade of 174 leaves

No GO_CENTRAL defect on this node, and no PSEUDOCAP defect on trpI.