GO_REF:0000118

TreeGrafter-generated GO annotations

GO_REF:0000120

Combined Automated Annotation using Multiple IEA Methods

file:PSEPK/PP_0312/PP_0312-uniprot.txt

UniProtKB entry for PP_0312 (Q88R22)

Q88R22 carries ETF alpha-subunit family and domain signatures; the record has no curated function.

file:PSEPK/PP_0312/PP_0312-bioinformatics/RESULTS.md

PP_0312 / PP_0313: dimethylglycine-locus ETF versus canonical ETF paralogs

PP_0312 is 65.5% identical to Chromohalobacter dgc-locus EtfA but about 33-35% identical to KT2440 PP_4201 and human ETFA, which are 62.1% identical to each other.

PMID:32631860

Role of N,N-Dimethylglycine and Its Catabolism to Sarcosine in Chromohalobacter salexigens DSM 3043.

Disruption and complementation show that all four Chromohalobacter locus genes participate in dimethylglycine conversion; transfer of the pathway role to PP_0312 depends on conserved synteny and orthology.

"the csal_0990, csal_0991, csal_0992, and csal_0993 genes are responsible for DMG degradation to sarcosine."

PMID:8962055

Three-dimensional structure of human electron transfer flavoprotein to 2.1-A resolution.

Human ETF structure; FAD resides mostly in the C-terminal portion of the alpha subunit.

"FAD lies in a cleft between the two subunits, with most of the FAD molecule residing in the C-terminal portion of the alpha subunit."