Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Inter-organelle lipid transfer: a channel model for Vps13 and chorein-N motif proteins.
VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites.
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An N-terminal fragment of S. cerevisiae Vps13 (residues 1-1350) binds about ten glycerophospholipids per molecule and transfers glycerolipids between membranes in vitro.
"Thus, in vitro transfer assays showed that Vps13α can transfer glycerolipids between membranes in vitro."
Cryo-EM reconstruction of a VPS13 fragment reveals a long groove to channel lipids between membranes.
Yeast Vps13 promotes mitochondrial function and is localized at membrane contact sites.
ER-mitochondrial junctions can be bypassed by dominant mutations in the endosomal protein Vps13.
Vps13-Mcp1 interact at vacuole-mitochondria interfaces and bypass ER-mitochondria contact sites.
Competitive organelle-specific adaptors recruit Vps13 to membrane contact sites.
The Vps13p-Cdc31p complex is directly required for TGN late endosome transport and TGN homotypic fusion.
The GTPase Arf1 Is a Determinant of Yeast Vps13 Localization to the Golgi Apparatus.
Vps13 is required for the packaging of the ER into autophagosomes during ER-phagy.
VPS13 regulates membrane morphogenesis during sporulation in Saccharomyces cerevisiae.
Genome-wide screening for genes associated with FK506 sensitivity in fission yeast.
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S. pombe vps1302 deletion cells secrete about half the wild-type level of acid phosphatase, are moderately micafungin- and FK506-sensitive, and have normal vacuole fusion.
"Only 6 of the 16 genes (Aps3, Apl6, Vps1302, Vps71, Erv15 and Myo1) showed normal vacuole fusion."
Meiotic spindle pole bodies acquire the ability to assemble the spore plasma membrane by sequential recruitment of sporulation-specific components in fission yeast.
vps1302 bioinformatics results (Spo2 nesting and PANTHER placement)