Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Combined Automated Annotation using Multiple IEA Methods
ALG-2 interacts with the amino-terminal domain of annexin XI in a Ca(2+)-dependent manner.
The penta-EF-hand domain of ALG-2 interacts with amino-terminal domains of both annexin VII and annexin XI in a Ca2+-dependent manner.
Calcyclin (S100A6) regulates pulmonary fibroblast proliferation, morphology, and cytoskeletal organization in vitro.
Calcium- and cell cycle-dependent association of annexin 11 with the nuclear envelope.
Dissecting the cellular functions of annexin XI using recombinant human annexin XI-specific autoantibodies cloned by phage display.
Annexin 11 is required for midbody formation and completion of the terminal phase of cytokinesis.
Identification of Alix-type and Non-Alix-type ALG-2-binding sites in human phospholipid scramblase 3: differential binding to an alternatively spliced isoform and amino acid-substituted mutants.
Large-scale proteomics and phosphoproteomics of urinary exosomes.
S100A6 binds to annexin 2 in pancreatic cancer cells and promotes pancreatic cancer cell motility.
Defining the membrane proteome of NK cells.
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.
Widespread macromolecular interaction perturbations in human genetic disorders.
Proteomic characterization of human multiple myeloma bone marrow extracellular matrix.
Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
A reference map of the human binary protein interactome.
The 56K autoantigen is identical to human annexin XI.
Translocation of annexin XI to neutrophil subcellular organelles.
Calcium-dependent binding of sorcin to the N-terminal domain of synexin (annexin VII).
Subcellular - ANXA11 - The Human Protein Atlas
A new role for annexin A11 in the early secretory pathway via stabilizing Sec31A protein at the endoplasmic reticulum exit sites (ERES).
-
ANXA11 associates with the ERES coat component Sec31A through ALG-2; the abstract identifies ALG-2 as the bridging adaptor.
"annexin A11 (AnxA11), physically associates with Sec31A
by the adaptor function of ALG-2."
RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether.
ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes.
-
Purified human ANXA11 couples isolated RNP granules to model membranes, with full-length and negative-control dependence.
"Co-incubation of the FAPS-purified RNP granules with ANXA11-coated GUVs results in accumulation of the RNP granules onto the GUV surface"
Annexin A11 C-terminal domain reveals calcium-dependent co-binding to RNA and lipid vesicles.
-
The abstract reports simultaneous calcium-dependent C-terminal RNA and lipid-vesicle binding; construct species and full Methods remain unresolved.
"the ANXA11
Ct directly binds lipid vesicles and RNA simultaneously."
Sorcin couples Annexin A11 recruitment to ESCRT-III assembly for plasma membrane repair.
-
ANXA11 recruits sorcin to model membranes in a purified calcium-containing system, alongside human-cell recruitment evidence.
"sorcin binds directly and specifically to ANXA11 and that ANXA11 is sufficient to recruit sorcin to membranes in the presence of Ca2+"