Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Combined Automated Annotation using Multiple IEA Methods
A directed protein interaction network for investigating intracellular signal transduction.
Regulation of endoplasmic reticulum turnover by selective autophagy.
Role of FAM134 paralogues in endoplasmic reticulum remodeling, ER-phagy, and Collagen quality control.
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RETREG2/FAM134A is an ER-anchored autophagy regulator, inactive basally and activated by cellular stress, that induces ER fragmentation and delivers ER into lysosomes via autophagosomal sequestration (ATG8 interaction); FAM134 paralogues function in ER remodeling and collagen quality control.