Gene Ontology annotation through association of InterPro records with GO terms

Gene Ontology annotation based on Enzyme Commission mapping

Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Gene Ontology annotation based on curation of immunofluorescence data

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Automatic assignment of GO terms using logical inference, based on on inter-ontology links

Automatic Gene Ontology annotation based on Rhea mapping

Combined Automated Annotation using Multiple IEA Methods

Identification of human male germ cell-associated kinase, a kinase transcriptionally activated by androgen in prostate cancer cells.

Male germ cell-associated kinase, a male-specific kinase regulated by androgen, is a coactivator of androgen receptor in prostate cancer cells.

Exome sequencing and analysis of induced pluripotent stem cells identify the cilia-related gene male germ cell-associated kinase (MAK) as a cause of retinitis pigmentosa.

A novel mammalian protein kinase gene (mak) is highly expressed in testicular germ cells at and after meiosis.

Male germ cell-associated kinase is overexpressed in prostate cancer cells and causes mitotic defects via deregulation of APC/CCDH1.

Negative regulation of ciliary length by ciliary male germ cell-associated kinase (Mak) is required for retinal photoreceptor survival.

Ccrk-Mak/Ick signaling is a ciliary transport regulator essential for retinal photoreceptor survival.

MAK-deep-research-falcon.md