Gene Ontology annotation through association of InterPro records with GO terms

Annotation inferences using phylogenetic trees

Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara

Electronic Gene Ontology annotations created by ARBA machine learning models

Combined Automated Annotation using Multiple IEA Methods

The role of high molecular weight kininogen and prothrombin as cofactors in the binding of factor XI A3 domain to the platelet surface.

Crystal structures of the FXIa catalytic domain in complex with ecotin mutants reveal substrate-like interactions.

Crystal structure of the factor XI zymogen reveals a pathway for transactivation.

Solution structure of the A4 domain of factor XI sheds light on the mechanism of zymogen activation.

Large-scale proteomics and phosphoproteomics of urinary exosomes.

Inactivation of human plasma kallikrein and factor XIa by protein C inhibitor.

Hageman-factor-dependent fibrinolysis: generation of fibrinolytic activity by the interaction of human activated factor XI and plasminogen.

Modification of the N-terminus of human factor IX by defective propeptide cleavage or acetylation results in a destabilized calcium-induced conformation: effects on phospholipid binding and activation by factor XIa.

Molecular cloning of platelet factor XI, an alternative splicing product of the plasma factor XI gene.

factor XI + platelet glycoprotein (GP) Ib:IX:V complex -> factor XI:platelet glycoprotein (GP) Ib:IX:V complex

factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (XIIa catalyst)

factor IX -> factor IXa + factor IX activation peptide (factor XIa catalyst)

factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst)

factor XIa binds SERPING1

factor XIa binds SERPINE1

factor XIa binds APP(18-770)

FIX(29-461) variant is not activated (factor XIa catalyst)

factor XI:kininogen:GPIb:IX:V complex -> factor XIa:kininogen:GPIb:IX:V complex (XIIa catalyst)

FXI + kininogen -> FXI:kininogen

FXI:kininogen + GPIb:IX:V -> FXI:kininogen:GPIb:IX:V

A sequential mechanism for exosite-mediated factor IX activation by factor XIa.

Age-related changes in coagulation, fibrinolysis, and platelet aggregation in male WBN/Kob rats.

A monoclonal antibody to high-molecular weight kininogen is therapeutic in a rodent model of reactive arthritis.