Gene Ontology annotation through association of InterPro records with GO terms

Annotation inferences using phylogenetic trees

Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt

Electronic Gene Ontology annotations created by ARBA machine learning models

TreeGrafter-generated GO annotations

Combined Automated Annotation using Multiple IEA Methods

The POU factor Oct-25 regulates the Xvent-2B gene and counteracts terminal differentiation in Xenopus embryos.

Xenopus POU factors of subclass V inhibit activin/nodal signaling during gastrulation.

Sequential expression of multiple POU proteins during amphibian early development.

POU-V factors antagonize maternal VegT activity and beta-Catenin signaling in Xenopus embryos.

The Xenopus POU class V transcription factor XOct-25 inhibits ectodermal competence to respond to bone morphogenetic protein-mediated embryonic induction.

Oct25 represses transcription of nodal/activin target genes by interaction with signal transducers during Xenopus gastrulation.

Shared features of blastula and neural crest stem cells evolved at the base of vertebrates.

NEURODEVELOPMENT. Shared regulatory programs suggest retention of blastula-stage potential in neural crest cells.

Reactivation of the pluripotency program precedes formation of the cranial neural crest.

Pluripotency factors are repurposed to shape the epigenomic landscape of neural crest cells.

Suv4-20h histone methyltransferases promote neuroectodermal differentiation by silencing the pluripotency-associated Oct-25 gene.