"Wild-type HArab15 and its constitutively active, GTP-bound mutant (Q67L) reduce fluid phase and receptor-mediated endocytosis without affecting the rate of recycling from early endosomal compartments"

"Inhibition of early endocytosis appears to be due to a reduction in the rate of homotypic early endosome fusion"

"the two constitutively inactive mutants, GDP-bound HArab15-T22N and the non-nucleotide binding mutant HArab15-N121I, differentially regulate the transit of fluid phase and receptor-mediated endocytic tracers through early/sorting endosomes"

"HArab15 may counteract the reported stimulatory effect of Rab5 on early endocytosis"

"Our data indicate that HArab15 differentially regulates distinct steps in membrane trafficking through early/sorting and pericentriolar recycling endosomes"

"we identified the novel protein Rab15 effector protein (REP15) as a binding partner for Rab15-GTP"

"REP15 is compartment specific, colocalizing with Rab15 and Rab11 on the endocytic recycling compartment but not with Rab15, Rab4, or early endosome antigen 1 on sorting endosomes"

"REP15 overexpression and small interfering RNA-mediated depletion inhibited transferrin receptor recycling from the endocytic recycling compartment"

"REP15 overexpression and small interfering RNA-mediated depletion inhibited transferrin receptor recycling from the endocytic recycling compartment, without affecting receptor entry into or recycling from sorting endosomes"

"Our data identify REP15 as a compartment-specific protein for receptor recycling from the endocytic recycling compartment"

"To find Rabs involved in primary cilium formation, the 39 predicted human RabGAPs were tested for their ability to prevent primary cilium formation"

"Screening the human Rabs revealed that Rab8a was the only Rab that could be detected on primary cilia when expressed as a GFP-tagged protein"

"dominant-negative forms of Rab8a, -17, and -23, but not the other Rabs tested, including Rab8b, prevented primary cilium formation"

"Rab8a is the sole Rab on primary cilia"

"Here, we used LC-MS/MS to profile the proteome of human urinary exosomes"

"Overall, the analysis identified 1132 proteins unambiguously"

"exosome analysis is a potential approach to discover urinary biomarkers"

"Apart from Rab3 and Rab27, we identified three additional Rabs, Rab15 (a previously reported endocytic Rab), Rab33 and Rab37, on the WPB limiting membrane"

"A knockdown approach using siRNAs showed that among these five WPB Rabs only Rab3, Rab27 and Rab15 are required for exocytosis"

"Intriguingly, we found that Rab15 cooperates with Rab27a in WPB secretion"

"a specific effector of Rab27, Munc13-4, appears to be also an effector of Rab15 and is required for WPB exocytosis"

"WPB secretion requires the coordinated function of a specific group of Rabs"

"RAB15 localizes to sorting/early endosomes (SEs/EEs) and the perinuclear endocytic recycling compartment (ERC), where it co-resides with Rab4/5 on SEs and Rab11 on ERC"

"RAB15 regulates endocytic sorting and recycling of the transferrin receptor (TfR), helping partition cargo between rapid recycling from SEs and slower recycling via the ERC"

"REP15 was identified as a direct, specific RAB15 effector that prefers RAB15-GTP, colocalizes perinuclearly with RAB15, and regulates TfR recycling"