Autonomous flowering all-member review (2026-10-26)

Re-reviewed all 20 original rows and independently assessed the two inherited NEW molecular-function proposals. Real existing provider reports were used only to locate primary evidence. The old phosphatidylethanolamine-binding core quoted TFL1 antagonism and did not support its lipid claim. Direct primary PMID:24698997 reports no PE binding signal even at increased PE loading, specific PC binding, and liposome confirmation; PMID:31726375 provides structural modeling plus experimentally tested binding-site mutations. The original ISS PE row is therefore MODIFY to GO:0031210 phosphatidylcholine binding, preserving the original term/evidence/reference payload. The PC core uses those experiments. This is a ligand correction, not a new redundant lipid annotation; the PEBP family name is not experimental evidence of PE affinity.

The two inherited NEWs remain: PMID:16099979 establishes FT interaction with FD, and PMID:16099980 establishes AP1 activation by the FT-FD complex. GO:0140297 records specific partner recognition; GO:0003713 records the transcriptional coactivator effect. Live QuickGO ancestry checks show neither is an ancestor/descendant of the other. These are MF proposals, not process claims inferred from necessity or cargo transport. FT performs the coactivation step through its DNA-binding partner; it is not itself assigned DNA binding. No additional NEW row was created.

Full PMID:22529749 explicitly reports FT:RFP/FTIP1:GFP colocalization at ER connected to the nuclear envelope in transiently transformed N. benthamiana leaf epidermis. The ER term is retained KEEP_AS_NON_CORE with that assay boundary; the observation is not rejected merely because FT transcriptional action is nuclear. Cytoplasmic and nuclear locations remain supported. The source establishes FTIP1-mediated export, with FT as cargo/signal; neither FT transport activity nor a membrane-spanning FT topology is invented. The inherited proposed term for phloem protein transport was removed because FT is transported, and complex-assembly proposals were retired in favor of demonstrated coactivation and an explicit native-composition question.

Grafting/movement evidence comes from PMID:17446353, not the separately retracted FT-mRNA transport paper. Primary PMID:21737277 independently establishes the guard-cell stomatal function, which remains non-core. Meristem determinacy is supported by the genotype/tissue-expression/grafting comparisons in PMID:30943325 rather than inferred merely from flowering time.

Normal publication caching (just fetch-gene-pmids ARATH FT) completed. A targeted full-text refresh was interrupted by disk exhaustion before curated writes, then recovered serially after space was freed. Original source files were checked for intact metadata and abstracts; no cache text was edited manually. Existing real provider files were reused rather than fabricated or rewritten. Primary access levels below are those actually cached at final review.

Per-row audit

Row numbers are zero-based and identify the unchanged original order.

The original annotation payloads, including any NOT/contributes-to fields, were preserved. Existing annotations judged here are not cited as their own evidence. Provider-only warning suppression is not a reason to reintroduce provider prose as biological support.

Final local primary-source access

All cited primary caches were inspected at the stated access level; source-specific limits remain explicit in the review.

PR #5574 prose and justification follow-up

Corrected citation spacing in reviewer-authored prose without altering original annotation payloads, source quotations, raw source files or prior histories. Flower-development membership to positive regulation is explicitly a lateral role correction; unsigned regulation to positive regulation specifies the supported direction. FT/FD-dependent AP1 activation remains the evidence, without asserting new direct target assays.