Gene Ontology annotation through association of InterPro records with GO terms
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci.
Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding.
Mammalian class E vps proteins recognize ubiquitin and act in the removal of endosomal protein-ubiquitin conjugates.
TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation.
Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes.
The protein network of HIV budding.
Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins.
Physical and functional interactions between Daxx and TSG101.
Nedd4.1-mediated ubiquitination and subsequent recruitment of Tsg101 ensure HTLV-1 Gag trafficking towards the multivesicular body pathway prior to virus budding.
The human endosomal sorting complex required for transport (ESCRT-I) and its role in HIV-1 budding.
Identification and proteomic profiling of exosomes in human urine.
Interactions of TOM1L1 with the multivesicular body sorting machinery.
SIMPLE interacts with NEDD4 and TSG101: evidence for a role in lysosomal sorting and implications for Charcot-Marie-Tooth disease.
Towards a proteome-scale map of the human protein-protein interaction network.
Collection, storage, preservation, and normalization of human urinary exosomes for biomarker discovery.
The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor.
Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release.
HD-PTP and Alix share some membrane-traffic related proteins that interact with their Bro1 domains or proline-rich regions.
Spongiform neurodegeneration-associated E3 ligase Mahogunin ubiquitylates TSG101 and regulates endosomal trafficking.
Structural and biochemical studies of ALIX/AIP1 and its role in retrovirus budding.
Vps22/EAP30 in ESCRT-II mediates endosomal sorting of growth factor and chemokine receptors destined for lysosomal degradation.
Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis.
Involvement of vacuolar protein sorting pathway in Ebola virus release independent of TSG101 interaction.
Identification of human MVB12 proteins as ESCRT-I subunits that function in HIV budding.
Regulation of Tsg101 expression by the steadiness box: a role of Tsg101-associated ligase.
Identification of Alix-type and Non-Alix-type ALG-2-binding sites in human phospholipid scramblase 3: differential binding to an alternatively spliced isoform and amino acid-substituted mutants.
Differential requirements for Alix and ESCRT-III in cytokinesis and HIV-1 release.
Large-scale proteomics and phosphoproteomics of urinary exosomes.
An empirical framework for binary interactome mapping.
Penta-EF-hand protein ALG-2 functions as a Ca2+-dependent adaptor that bridges Alix and TSG101.
Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network.
TEX14 interacts with CEP55 to block cell abscission.
Membrane budding and scission by the ESCRT machinery: it's all in the neck.
Distinct functions of human MVB12A and MVB12B in the ESCRT-I dependent on their posttranslational modifications.
The role of ESCRT proteins in fusion events involving lysosomes, endosomes and autophagosomes.
UBAP1 is a component of an endosome-specific ESCRT-I complex that is essential for MVB sorting.
Structural basis for membrane targeting by the MVB12-associated β-prism domain of the human ESCRT-I MVB12 subunit.
Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein.
Syndecan-syntenin-ALIX regulates the biogenesis of exosomes.
Monitoring the Rab27 associated exosome pathway using nanoparticle tracking analysis.
Charcot-Marie-Tooth disease-linked protein SIMPLE functions with the ESCRT machinery in endosomal trafficking.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles.
A proteome-scale map of the human interactome network.
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Pooled-matrix protein interaction screens using Barcode Fusion Genetics.
Architecture of the human interactome defines protein communities and disease networks.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
A reference map of the human binary protein interactome.
A helical assembly of human ESCRT-I scaffolds reverse-topology membrane scission.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs.
Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions.
A comprehensive two-hybrid analysis to explore the Legionella pneumophila effector-effector interactome.
Multimodal cell maps as a foundation for structural and functional genomics.
TSG101 may be the prototype of a class of dominant negative ubiquitin regulators.
Monoubiquitinated N-myristoyl GAG polyprotein is targeted to the late endosomal vesicle membrane by the ESCRT-I complex
Transport of GAG to the Plasma Membrane
Recruitment Of HIV Virion Budding Machinery
Cargo Recognition And Sorting
Rab5-dependent autophagosome closure by ESCRT.
VPS37A directs ESCRT recruitment for phagophore closure.
UniProtKB record for human TSG101