Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
UniProtKB record for gp38 (P03739)
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gp38 is a chaperone involved together with gp57 in the assembly of the distal-half tail fiber of bacteriophage T4.
"Chaperone involved, together with gp57, in the assembly of"
Deep research review for bacteriophage T4 gene 38 (gp38)
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gp38 is required together with gp57A for the folding and trimeric assembly of the distal long tail fiber adhesin gp37.
"Multiple independent sources converge that **T4 gp38 is required for correct folding and trimeric assembly of gp37**, the distal LTF protein."
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gp38 acts intracellularly during morphogenesis and is absent from mature T4 virions.
"The dominant model for T4 is that gp38 acts during **intracellular assembly/morphogenesis** of LTF components and is **not incorporated into the mature T4 long tail fiber** (nor detected in mature virions), consistent with its role as a chaperone rather than a structural receptor-binding adhesin in T4."