Gene Ontology annotation through association of InterPro records with GO terms
Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
UniProtKB entry for PSEPK LysA-I
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Assigns Q88L58 to EC 4.1.1.20, the LysA-specific family, and the terminal conversion of meso-diaminopimelate to L-lysine.
"Full=Diaminopimelate decarboxylase"
QuickGO annotation snapshot for PSEPK LysA-I
OpenScientist literature and database synthesis for PSEPK LysA-I
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Corroborates Q88L58/PP_2077 as the PLP-dependent EC 4.1.1.20 enzyme for the terminal decarboxylation in L-lysine biosynthesis.
"Q88L58 (lysA-I / PP_2077) is a PLP-dependent diaminopimelate decarboxylase catalyzing the final step of lysine biosynthesis."
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No direct Q88L58 characterization was found, so target-specific kinetics, regulation, structure, essentiality, and relative flux versus Q88CF4 remain unverified.
"No direct experimental characterization of Q88L58."
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Proposed LysR regulation, a parallel DapL route, and gene-specific antibacterial essentiality are not adopted because they are based on genomic context, database mapping, or other organisms rather than a direct KT2440 experiment.