H1-4 source guide

The source-evidence file records original access, selected sections, phylogenetic assertions, assay records and typed ontology paths. Normal cache availability and external original access are recorded separately.

PMID:22681889

The authentic abstract describes UV cross-linking and oligo(dT) enrichment. Publisher access failed; the author-thesis response was a bot-check page. No target-table verification is claimed.

PMID:17474147

IntAct identifies human H1.4 peptide178–190 and NCK1 SH3 fragments in vitro. The paper's PLCG1 full-protein validation is not H1.4–NCK1 validation.

PMID:17540172

Official H1b identity and the original abstract support association. IntAct separately records HEK293 co-IP and methylated-peptide pull-downs; original figures were not accessed.

PMID:28514442

Human ORFeome baits were expressed in HEK293T for AP-MS. Co-complex recovery does not establish purified pairwise binding.

PMID:30021884

Original Methods identify U2OS isolated nuclei and DSSO cross-linking. Six exact IntAct pairs were replayed; independent spectra were not reanalyzed.

PMID:33961781

Human ORFeome FLAG-HA baits were analyzed separately in 293T and HCT116. Exact target pairs are present in IntAct; co-recovery is not purified binary binding.

PMID:34232536

The exact target record specifies HEK293T tandem affinity purification, distinct from the paper's separate BioID experiments.

PMID:34901782

Original HEK293 EGFP-bait AP-MS used benzonase before purification. This does not alone prove direct binary affinity.

PMID:35271311

Original OpenCell Methods describe endogenous fluorescent tags and digitonin IP-MS in HEK293T. The full target inventory was not independently replayed.

PMID:36217030

Results23, Methods59 and Figure2h explicitly validate the H1.4–N interaction; viral replication involvement is proposed, not demonstrated for H1.4.

PMID:36950384

Original Methods use endogenous immunoprecipitation in four-week human iPSC-derived neurons. SYNGAP1 target-table details remain curator-supported rather than independently replayed.

PMID:15469825

The authentic abstract reports H1 interaction and deacetylation by SIRT1. Official P10412 provenance identifies Lys26; full experimental methods remain inaccessible.

Primary access and provenance

See source evidence for the seven primary-source readings and original capture URLs and hashes, and input evidence for every incoming record and its current review. The two retained GO-CAM activities cite the same paper; they are not independent experiments.