Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins.
The SMN complex, an assemblyosome of ribonucleoproteins.
Complete sequencing and characterization of 21,243 full-length human cDNAs.
The DNA sequence and comparative analysis of human chromosome 5.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Specific sequence features, recognized by the SMN complex, identify snRNAs and determine their fate as snRNPs.
Quantitative proteomics identifies Gemin5, a scaffolding protein involved in ribonucleoprotein assembly, as a novel partner for eukaryotic initiation factor 4E.
The Gemin5 protein of the SMN complex identifies snRNAs.
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
A comprehensive interaction map of the human survival of motor neuron (SMN) complex.
The full-ORF clone resource of the German cDNA Consortium.
A quantitative atlas of mitotic phosphorylation.
Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs.
Gemin5-snRNA interaction reveals an RNA binding function for WD repeat domains.
Identification of gemin5 as a novel 7-methylguanosine cap-binding protein.
Defining the membrane proteome of NK cells.
Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
Gemin5 delivers snRNA precursors to the SMN complex for snRNP biogenesis.
Initial characterization of the human central proteome.
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Toward a comprehensive characterization of a human cancer cell phosphoproteome.
Gemin5 Binds to the Survival Motor Neuron mRNA to Regulate SMN Expression.
The RNA-binding protein Gemin5 binds directly to the ribosome and regulates global translation.
Structural basis for specific recognition of pre-snRNA by Gemin5.
Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly.
Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5.
Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
Architecture of the human interactome defines protein communities and disease networks.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Loss of function mutations in GEMIN5 cause a neurodevelopmental disorder.
The RBS1 domain of Gemin5 is intrinsically unstructured and interacts with RNA through conserved Arg and aromatic residues.
OpenCell: Endogenous tagging for the cartography of human cellular organization.
Multimodal cell maps as a foundation for structural and functional genomics.
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Gene Ontology annotation based on curation of immunofluorescence data
Electronic Gene Ontology annotations created by ARBA machine learning models
snRNP:Snurportin complex formation
snRNA Cap hypermethylation
Loading and methylation of Sm proteins onto SMN Complexes
snRNP nuclear import and release
SARS-CoV-2 modulates host translation machinery
Eukaryotic translation initiation factor 4E
Small nuclear ribonucleoprotein-associated proteins B and B'
Small nuclear ribonucleoprotein E
Small nuclear ribonucleoprotein Sm D1
Small nuclear ribonucleoprotein Sm D2
Small nuclear ribonucleoprotein Sm D3
Survival motor neuron protein
Probable ATP-dependent RNA helicase DDX20
UniProtKB entry Q8TEQ6 (GEMI5_HUMAN)
Falcon (Edison) deep research report on human GEMIN5
Selected primary evidence for GEMIN5
Gemin5 promotes IRES interaction and translation control through its C-terminal region.