GO_REF:0000033
Annotation inferences using phylogenetic trees
GO_REF:0000044
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
PMID:10970873
Neuralized functions cell autonomously to regulate Drosophila sense organ development.
PMID:11180964
neuralized functions cell-autonomously to regulate a subset of notch-dependent processes during adult Drosophila development.
PMID:11344304
Neuralized is essential for a subset of Notch pathway-dependent cell fate decisions during Drosophila eye development.
PMID:11696324
Neuralized functions as an E3 ubiquitin ligase during Drosophila development.
PMID:11740940
Drosophila neuralized is a ubiquitin ligase that promotes the internalization and degradation of delta.
PMID:12852858
Unequal segregation of Neuralized biases Notch activation during asymmetric cell division.
PMID:15113404
The roles of cis-inactivation by Notch ligands and of neuralized during eye and bristle patterning in Drosophila.
PMID:15760269
Two distinct E3 ubiquitin ligases have complementary functions in the regulation of delta and serrate signaling in Drosophila.
PMID:15829515
The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta.
PMID:15901829
Regulation of membrane localization of Sanpodo by lethal giant larvae and neuralized in asymmetrically dividing cells of Drosophila sensory organs.
PMID:15930117
Distinct roles for Mind bomb, Neuralized and Epsin in mediating DSL endocytosis and signaling in Drosophila.
PMID:16093323
The interplay between DSL proteins and ubiquitin ligases in Notch signaling.
PMID:16459303
Bearded family members inhibit Neuralized-mediated endocytosis and signaling activity of Delta in Drosophila.
PMID:17065551
The NHR1 domain of Neuralized binds Delta and mediates Delta trafficking and Notch signaling.
PMID:17070683
Stem cells signal to the niche through the Notch pathway in the Drosophila ovary.
PMID:18061562
Neuralized contains a phosphoinositide-binding motif required downstream of ubiquitination for delta endocytosis and notch signaling.
PMID:18794519
Neuralized is expressed in the alpha/beta lobes of adult Drosophila mushroom bodies and facilitates olfactory long-term memory formation.
PMID:1913825
A role for the Drosophila neurogenic genes in mesoderm differentiation.
PMID:19580805
Both inhibition and activation of Notch signaling rely on a conserved Neuralized-binding motif in Bearded proteins and the Notch ligand Delta.
PMID:21912646
Comprehensively surveying structure and function of RING domains from Drosophila melanogaster.
PMID:22162135
Distinct intracellular motifs of Delta mediate its ubiquitylation and activation by Mindbomb1 and Neuralized.
PMID:24318532
An unexpected link between notch signaling and ROS in restricting the differentiation of hematopoietic progenitors in Drosophila.
PMID:26092715
Novel Genes Involved in Controlling Specification of Drosophila FMRFamide Neuropeptide Cells.
PMID:26659188
Polarized endosome dynamics by spindle asymmetry during asymmetric cell division.
PMID:28306050
A late role for a subset of neurogenic genes to limit sensory precursor recruitments in Drosophila embryos.
PMID:28400441
Neuralized regulates Crumbs endocytosis and epithelium morphogenesis via specific Stardust isoforms.
PMID:28960177
Ubiquitylation-independent activation of Notch signalling by Delta.
PMID:8060613
Mutations affecting the pattern of the PNS in Drosophila reveal novel aspects of neuronal development.
Reactome:R-DME-209226
DL/SER is ubiquitinated by E3 ubiquitination ligases (NEUR/MIB1)
file:DROME/neur/neur-deep-research-falcon.md
Deep research report on Drosophila neur (Falcon)