Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies.
Desmuslin, an intermediate filament protein that interacts with alpha -dystrobrevin and desmin.
Interactions between epiplakin and intermediate filaments.
Cytoskeletal scaffolding proteins interact with Lynch-Syndrome associated mismatch repair protein MLH1.
Myotubularin controls desmin intermediate filament architecture and mitochondrial dynamics in human and mouse skeletal muscle.
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
Nebulin binding impedes mutant desmin filament assembly.
The novel desmin mutant p.A120D impairs filament formation, prevents intercalated disk localization, and causes sudden cardiac death.
Interaction of plectin with keratins 5 and 14: dependence on several plectin domains and keratin quaternary structure.
The toxic effect of R350P mutant desmin in striated muscle of man and mouse.
A proteome-scale map of the human interactome network.
A novel phosphorylation site, Serine 199, in the C-terminus of cardiac troponin I regulates calcium sensitivity and susceptibility to calpain-induced proteolysis.
Functional characterization of the novel DES mutation p.L136P associated with dilated cardiomyopathy reveals a dominant filament assembly defect.
Homologous Transcription Factors DUX4 and DUX4c Associate with Cytoplasmic Proteins during Muscle Differentiation.
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Pooled-matrix protein interaction screens using Barcode Fusion Genetics.
Nebulette is a powerful cytolinker organizing desmin and actin in mouse hearts.
αB-crystallin is a sensor for assembly intermediates and for the subunit topology of desmin intermediate filaments.
Architecture of the human interactome defines protein communities and disease networks.
A reference map of the human binary protein interactome.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Spatial and temporal expression of the beta1D integrin during mouse development.
Missense mutations in desmin associated with familial cardiac and skeletal myopathy.
A dysfunctional desmin mutation in a patient with severe generalized myopathy.
Release Of ADP From Myosin
Desmin enters the nucleus of cardiac stem cells and modulates Nkx2.5 expression by participating in transcription factor complexes that interact with the nkx2.5 gene.
Loss of Nuclear Envelope Integrity and Increased Oxidant Production Cause DNA Damage in Adult Hearts Deficient in PKP2: A Molecular Substrate of ARVC.
Ultrastructural and biochemical localization of N-RAP at the interface between myofibrils and intercalated disks in the mouse heart.
Association of syncoilin and desmin: linking intermediate filament proteins to the dystrophin-associated protein complex.
A Balance Between Intermediate Filaments and Microtubules Maintains Nuclear Architecture in the Cardiomyocyte.
DES source evidence and original-access notes