Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Electronic Gene Ontology annotations created by ARBA machine learning models
Combined Automated Annotation using Multiple IEA Methods
her1 and her13.2 are jointly required for somitic border specification along the entire axis of the fish embryo.
Coordination of symmetric cyclic gene expression during somitogenesis by Suppressor of Hairless involves regulation of retinoic acid catabolism.
-
Combined Su(H) knockdown disrupts L/R asymmetry, lateral inhibition and the segmentation oscillator.
"Combined Su(H) gene knockdown caused defects in visceral left/right asymmetry, neurogenic lateral inhibition, and symmetrical failure of the segmentation oscillator."
Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries.
Notch signalling regulates left-right asymmetry through ciliary length control.
Wt1a, Foxc1a, and the Notch mediator Rbpj physically interact and regulate the formation of podocytes in zebrafish.
-
Zebrafish Rbpj binds NICD and physically interacts with Wt1a and Foxc1a.
"Wt1a, Foxc1a, and Rbpj can physically interact with each other, whereas only Rbpj binds to the Notch intracellular domain (NICD)"
Analysis of Dll4 regulation reveals a combinatorial role for Sox and Notch in arterial development.
Falcon (Edison Scientific Literature) deep research report for Danio rerio rbpjb (A4FTT4)
-
rbpja/rbpjb paralog-specific roles are rarely distinguished in the literature.
"The available literature confirms this paralog pair but rarely distinguishes their individual biochemical or developmental"