Gene Ontology annotation through association of InterPro records with GO terms
Annotation inferences using phylogenetic trees
Gene Ontology annotation based on curation of immunofluorescence data
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Combined Automated Annotation using Multiple IEA Methods
A visual intracellular classification strategy for uncharacterized human proteins.
Translokin is an intracellular mediator of FGF-2 trafficking.
Tsp57: a novel gene induced during a specific stage of spermatogenesis.
Proteomic characterization of the human centrosome by protein correlation profiling.
Systematic identification of hepatocellular proteins interacting with NS5A of the hepatitis C virus.
A comprehensive resource of interacting protein regions for refining human transcription factor networks.
Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.
Next-generation sequencing to generate interactome datasets.
A proteome-scale map of the human interactome network.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
Spatial centrosome proteome of human neural cells uncovers disease-relevant heterogeneity.
AJUBA facilitates AURKA autophosphorylation
AJUBA binds centrosome-associated AURKA
AURKA phosphorylates PLK1
BORA binds PLK1 and AURKA
Plk1-mediated phosphorylation of Nlp
Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome
Loss of C-Nap-1 from centrosomes
Dissociation of Phospho-Nlp from the centrosome
Recruitment of Plk1 to centrosomes
Association of NuMA with microtubules
Recruitment of CDK11p58 to the centrosomes
Translocation of NuMA to the centrosomes
RAB3IP stimulates nucleotide exchange on RAB8A
C2CD3 binds the mother centriole
C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole
CP110 and CEP97 dissociate from the centriole
The distal appendage proteins recruit TTBK2
Recruitment of transition zone proteins
MARK4 binds ODF2 in the centriole
CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body
TPX2 binds AURKA at centrosomes
TPX2 promotes AURKA autophosphorylation
Cep57, a multidomain protein with unique microtubule and centrosomal localization domains.
Cep57, a NEDD1-binding pericentriolar material component, is essential for spindle pole integrity.
The Cep57-pericentrin module organizes PCM expansion and centriole engagement.
Cep57 regulates human centrosomes through multivalent interactions.
Cep57 is a Mis12-interacting kinetochore protein involved in kinetochore targeting of Mad1-Mad2.
Cep57 protein is required for cytokinesis by facilitating central spindle microtubule organization.
Xenopus Cep57 is a novel kinetochore component involved in microtubule attachment.
Mutations in CEP57 cause mosaic variegated aneuploidy syndrome.