Identity
- Amidase-family GatA subunit of mitochondrial GatCAB (human QRSL1 ortholog).
[file:DROME/GatA/GatA-uniprot.txt "This subunit probably catalyzes the hydrolysis"].
- Fly naming: PMID:26761199;
pathway: PMID:26761199.
- Mitochondrial: IDA from the Liao et al. screen PMID:16849596 (abstract only cached).
- Serine hydrolase HDA (PMID:33827210, ABPP atlas): GatA not visible in cached text; amidase-signature
enzymes use a Ser nucleophile so FP-probe labelling is expected; kept non-core.
Decisions (module dmel_glutamyl_trna_amidotransferase, consistent across GatA/B/C)
- Complex, mitochondrion/matrix, contributes_to GO:0050567: ACCEPT.
- Obsolete GO:0070681: MODIFY -> GO:0043685 conversion of glutamyl-tRNA to glutaminyl-tRNA
(GO obsoletion comment says annotations need review, no automatic replacement).
- Mitochondrial translation: KEEP_AS_NON_CORE (real but downstream; the step is GO:0043685).
- Generic catalytic activity -> MODIFY to glutaminase activity; glutaminase activity ACCEPT.
Deep research (falcon)
- GatA was previously named benedict (bene); bene/gatA mutants (Genetics 2008) show growth defects in mitotic and endoreplicating tissues (not cached; cited by deep research): [file:DROME/GatA/GatA-deep-research-falcon.md "found GatA to be the only obvious fly ortholog of this amidotransferase subunit"].